Abstract
Passive agglutinations using latex particles or formol-alcohol-treated tanned sheep cells were compared with the conventional tests of leukocyte agglutination, complement fixation, and anti-globulin consumption, and were found to excel these tests in simplicity and specificity. Application of passive agglutinations will prove quite useful for the detection of leukocyte antibodies in routine screening.
The patient's serum which contained leukocyte antibodies was fractionated with DEAE cellulose into IgG, IgA, and IgM. Passive agglutination activities were found in the IgG and IgM, while no activity was detected in the IgA fraction.
