Abstract
The results of 68 leukocyte cross-matching procedure have been assessed in order to select compatible donors for 19 febrile granulocytopenic patients with acute leukemia.
It was revealed that there was positive relationship between precounts of patients' own leukocytes and granulocyte recovery rates. This phenomenon suggested that leukocytes of marginal pool were markedly depleted and most part of transfused granulocytes might marginate along the vessel walls in leukopenic patients.
This study confirms the clinical value of lymphocytotoxicity test (LCT) in predicting the post-transfusion recovery rate of single donor granulocytes. There was a good agreement between the LCT croos-match and granulocyte recovery. In general, compatibility in the granulocytotoxicity (GCT) has not any significant value in granulocyte recovery rates.
