血小板保存液“セト液”の臨床使用
1994 年 40 巻 4 号 p. 589-592
詳細
1994 年 40 巻 4 号 p. 589-592
In order to prevent adverse effects associated with the transfusion of platelet concentrates, the plasma in platelet concentrates was removed into another bag connected with a sterile connecting device and platelets were resuspended in the Seto solution. Average percentages of the plasma removal and the recovery of platelet were 94.4% and 93.8%, respectively. Platelets suspended in Seto solution were transfused 131 times into 22 patients who had showed adverse effects such as fever and urticarial rash and might exhibit hemolysis due to ABO-incompatible platelet transfusion. The average recovery of transfused platelets in vivo was 53% one day after platelet transfusion. This value was similar to that of the transfusion of platelet concentrates (55%). The adverse effects associated with platelet transfusions were remarkably decreased using Seto solution but developed in 2 cases. These results indicate that Seto solution is very useful to prevent the adverse effects due to plasma components.
