Abstract
In order to investigate the occurrence of several cases of supposed or suspected infection of malaria after transfusion of preserved blood, the author studied survival of plasmodia in preserved blood in the following experiments, using mainly Plasmodium berghei (Vincke and Lips) in mice and Plasmodium vivax in humans.
1. Plasmodium berghei seemed to preserve its infectivity to mice up to the 3rd day in stored blood after inoculation with anticoagulant Formula B, up to the 2nd day in the same with anticoagulant Formula A and up to the 5th day with simple sodium citrate.
2. The infectivity of P. berghei seemed to depend upon the dose of the pathogens.
3. In using Plasmodium vivax to human for therapeutic purpose, 2 of 4 recipients showed positive symptoms of infection, who received the contaminated blood preserved with ACD Formula B for 4 days. The incubation period in the other 2 patients was 16 and 17 days after the inoculation respectively.
