Abstract
A 31-day-old Japanese Black female calf was admitted to the Large Animal Treatment Center of Kitasato University because her wheezing, which had been treated with an tibiotics and corticosteroids from 14 to 25 days of age, had relapsed. Wheezing, labored respiration,anorexia and exercise intolerance were seen at the initial visit. Endoscopic examination showed hyperemia of the laryngopharynx mucosa, and bilateral arytenoid cartilage paralysis with the right arytenoid cartilage swollen and medially displaced. The calf was therefore diagnosed with pharyngolaryngitis, and given the following treatment. The antibiotic used and daily dose (treatment period) were cefazolin 1 g (day 1-2), enrofloxacin 200 mg (day 3-22), lincomycin 400 mg (day 3-27), tylosin 800 mg (day 32-44), and oxytetracycline 400 mg (day 46-54). Prednisolone 20 mg (day 1-5), 10 mg (day 6-11), 5mg (day 12-15) was administered by intramuscular injection, and flunixin 140 mg (day 16-22) was administered by intravenous injection, as antiinflammatory drugs. Inhalation treatment with kanamycin 250 mg or gentamicin 50 mg and a bronchodilator was also performed. Povidone iodine was applied to the laryngopharynx. The wheezing and appetite improved by day 6. By day 16, there was no wheezing except at feeding, and wheezing disappeared completely by day 54. These results suggest that long-term administration of antibiotics and antiinflammatory drugs is effective in treating wheezing caused by pharyngolaryngitis.
