Improvement of lipid peroxide by periodontal treatment in diabetic patients.

Abstract

To investigate the role of periodontal disease on atherosclerosis, we assessed the effects of periodontal treatment on lipid peroxide (LPO) in diabetic patients comparing non- diabetic patients. Five diabetic patients (age 49.2 years- old, male 4 female 1) and six non- diabetic patients (age 60.4 years- old, male 2, female 4) were given periodontal treatment. After the treatment, periodontal pocket depth and bleeding on probing were improved in both groups. LPO in diabetic group and anti- MDA- LDL antibody in both groups were significantly decreased. Periodontal treatment is useful to improve oxidative stress and expected to prevent the atherosclerosis in diabetes mellitus.