The Journal of Kansai Medical University
Online ISSN : 2185-3851
Print ISSN : 0022-8400
ISSN-L : 0022-8400
Clinical Evaluation of Fluothane-Ether (Azeotropic Mixture) Anesthesia
Junko Takeuchi
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1960 Volume 12 Issue 3 Pages 317-321

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Abstract
Fluothane-new nonexplosive anesthetic agent tends to cause hypotension, bradycardia and respiratory depression. One part of ether was mixed with two parts fluothane to correct these disadvantages. This compound resulted azeotropic mixture with boiling point at 51.5°C.
Thirty patients were anesthetized with azeotropic mixture from Forreger's copper kettle vaporizer and the inhalation of 1-2 % vapor mixture was sufficient to produce surgical anesthesia. The change of blood pressure was minimum and normal EKG was obtained, however, alveolar and blood CO2 were moderately increased. The recovery was rapid and no serious post-operative complication was observed.
In conclusion azeotropic mixture is potent, safe, nonexplosive anesthetic with less untoward effect on cardiovascular system than fluothane and this agent deserves more extended use in clinical anesthesia.
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© The Medical Society of Kansai Medical University
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