The Effect of Prednisone on Tuberculine Sensitivity during Chemotherapy
1963 Volume 15 Issue 1 Pages 55-57
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1963 Volume 15 Issue 1 Pages 55-57
Since it's discovery, prednisone, combined with chemotherapy, is often used for the treatment of tuberculosis. It has become one of the important agents in the treatment of acute tuberculosis or tuberculous meningitis where the patient is in the acute stage.
It has also been used for the treatment of children's pulmonary tuberculosis, and the reports have shown fair results.
We were interested in knowing if there were any effects on tuberculine sensitivity during the use of this agent combined with chemotherapy on tuberculous patients.
Eight patients were selected for this purpose because of positive tuberculine reaction even after chemotherapy for eight months.
5mg Qid, for four days,10mg Tid, for three days of prednisone were ordered. On the fifth day after prednisone treatment was started, Mantoux 1: 10,000 OT was tested on each patient.
We know that short term prednisone combined with chemotherapy will depress tuberculine sensitivity in some patients, however not in all.
