Report on A Case of Severe Agranurocytosis Induced by Methylthiouracil which Showed Leukemoid Reaction in Its Convalescent Stage

Abstract

A case of severe agranulocytosis with leukemoid reaction induced by methylthiouracil was reported. The patient was a 26 years old nurse suffering from hyperthyroidism. She was admitted to our clinic with complaints of high fever and sore throat. From her history and laboratory findings, this: case was diagnosed as agranulocytosis induced by Methyl-thiouracil. The patient was successfully treated with ACTH, steroid hormone and fresh-blood-transfusion from a chronic myeloic leukemia patient. Leukemoid reaction was recognized in her convalescent stage.