Recent progress in respiratory physiology related to anesthesia

Abstract

The relationship between oxygen content and oxygen partial pressure in blood was discussed with reference to the dissociation curve of hemoglobin. The importance of the establishment of membrane covered O₂-electrode (Clark electrode) in the field of respiratory physiology was emphasized. Intrapulmonary shunting was discussed in relation to Pao₂ and AaDo₂. At the same time, alveolar oxygen tension was discussed theoretically in each state of inhaling various concentration of oxygen in the inspiratory gases. The important role of oxygen content of mixed venous blood on analyses of Q_s/Q_r was interpreted. The effects of cardiac output on AaDo₂ and Pao₂ at each level of Q_s/Q_r were discussed and graphic representation was shown.
Relationship between arterial oxygen tension and age during postoperative course in the patients operated upper abdominal surgery was analyzed. The regression line and the formula were presented. At she same time, statistical analyses were studied and its significance on medical practice was discussed.