Amyloid and. Transfer Amyloid Induction in ICR/JCL Mice by Azocasein Administration in Comparison with Fe-NTA-induced “F₁ Amyloidosis” and Related Transfer Amyloidosis

Abstract

In comparison with the fact that more th an 49 injections of azocasein antigenicity was sufficient for amyloid and transfer amyloidosis induction in ICR/JCL mice, while Fe-NTA appears to be too weak an antigen as to provoke amyloidosis in the same strain of mice, although it can induce “F₁ amyloidosis” propably as a result of a secondary immune response. The results are discussed in terms of the antigenicity of azo casein as well as Fe-NTA in the experimental induction of transfer amyloidosis.