Effects of TRH-T and DN-1417 on Photopalpebral Reflex and Microvibration

Motohiro Yasuhara; Hiroe Naito; Kyoko Takemura; Masahisa Sawada; Naoko Takeda; Tomoko Yamamoto

doi:10.5361/jkmu1956.36.Supplement_s17

Motohiro Yasuhara, Hiroe Naito, Kyoko Takemura, Masahisa Sawada, Naoko Takeda, Tomoko Yamamoto

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Keywords: photopalpebral reflx, microvibration, brainstem, reticular, formation, TRH-T, DN-1417

JOURNAL FREE ACCESS

1984 Volume 36 Issue Supplement Pages s17-s29

DOI https://doi.org/10.5361/jkmu1956.36.Supplement_s17

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Abstract

We studied the effects of TRH and DN-1 417 on the PPR and MV of rabbits and obtained the following results:
1. TRH had a stronger facilitating activity on the central components, such as, PPR₅, PPR₇and PPR₈, among various components of PPR.
2. DN-1417 had a facilitating activity on such components of PPR₅, PPR₆, PPR₇ and PPR₈ but its activity was weaker than that of TRH.
3. TRH and DN-1417 also showed facilitating effects for individual components of MV but the activity was stronger with TRH than with DN-1417.
These results suggest that TRH has a stro nger facilitating activity on the nervous activity involving tissues other than the brainstem reticular formation than DN-1417.

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