1957 Volume 9 Issue 3 Pages 146-149
The Function of reticuloendothelial System of individual rabbits estimated by congo red method is fluctuating in a certain range under normal conditions.
The influence of multin which has been known as a unspecific immunantigen on the fluctuation of reticuloendothelial system was observed on each different rabbit.
The results obtained were as follows:
1) In case multin is intravenously injected on a rabbit, it some times increases the function of reticuloendothelial system. The increase is often accellated by the injection and falls down into normal range or below it in a short time, after which it some times rises or does not rise.
2) The effect of multin injection on reticuloendothelial system is no relation with the proper value of the physiological congo-red index of the animal. There seems to be some unknown cause of the fluctuation due to the multin injection.