Abstract
Studies were made on the in vitro lysis of leucocytes by using 16 rabbits. (Three of them were injected subcutaneously with living tuberculous bacilli of H37RV strain; 7 of them venously with the same strain; 2 of them intrapulmonarily with death strain; and the rest of them were not given any kind of injection.)
The method used at this experiment is the same as descrived in the first report.
The results obtained are as follows:
1) The leucocyte of these tuberculous rabbits causes cytolysis in vitro following the addition of tuberculin.
2) No relation was found between the intensity of tuberculin reaction and the rate of leucocytolysis of respective tuberculous individual animals.
3) The cytolysis is not so remarkable in the case of the subcutaneously injected group of rabbits as in that of the venously injected ones.
4) The cytolysis is more remarkable in the cases of iritis, testitis, and otitis or the combination of them than in pulmonary tuberculosis only.
5) The imitate eosinophile leucocytes play a main role in the leucocytolysis. In conclusion, the same results were obtained by the experiments above mentioned as were obtained in the case of tnberculous patients.