Experimental-pathological Studies about the Influence of Sodium iodate.

Report II. On the Researches of the Liver and Kidney of Rabbits.

Abstract

4% sodium iodate was daily injected into the ear vein of the rabbits (7 whites and 5blacks) in the daily dose of lcc/kg for 7 days.
Several examinations were done about peripheral blood findings, histological and histochemical examinations about liver and kidney.
The main results were as follows: -General Observations:
1) There were found remarkable anamia after the application.
2) About percentage of several sorts of leucocytes, momocytosis was observed well-known. Histological and histochemical Observations:
3) There were cloudy swelling on the central zone of liver cells of white rabbits, but vacuolious degeneration and fatty deposits were found on the liver cells of the central zone of black one.
4) By Perls' method, there were found iron deposits on the liver cells and the epitheliums of proximal convolution of white rabbits, but black rabbits could not found.
5) By Okamoto-Utamura's method, there were copper deposits on the liver cells and the epitheliums of proximal convolution of one black rabbits, but not found in the white one
6) The decrease of PAS positive substances on the liver cells and the epitheliums of proximal convolution were found both in the white and black rabbits.
7) Phosphatase in the liver cells and the epitheliums of proximal convolution of white and black rabbits were slightly increased after the application.