Chronic wounds of the lower extremities healing with artificial dermis

Abstract

The artificial dermis is established therapy for more than 20 years. It’s suitable for use in full thickness skin defect wounds and formation of new dermis-like tissue. Operation at chronic wounds of the lower extremities is usually two-stage operation. Wounds exposed muscle, tendon and bone after first operation suit for using artificial dermis. Using negative pressure wound therapy and basic fibroblast growth factor with artificial dermis shape better dermis-like tissue. Artificial dermis will function as release and delivery system of factor in future.