Abstract
We have experienced 3 cases of blood disorder-related acute limb ischemia. In cases 1 and 2, the patients were diagnosed with idiopathic thrombocytopenic purpura. After a thrombopoietin receptor agonist was administered, acute limb ischemia occurred. In both cases, the patients’ platelet counts were within normal limits. Thus, it is suggested that multiple factors including the administration of thrombopoietin receptor agonists can induce thrombosis. In case 3, acute limb ischemia occurred in a patient with myeloproliferative disease. Although revascularization alone was not effective, combination treatment with phlebotomy and hydroxyurea decreased the patient’s blood viscosity and improved their condition.
