Abstract
In this study, the effect on collagen gel contractions induced by a mesenchymal cell, such as an osteoblast, under the high magnetic fields and the addition of bioceramics was investigated. The biological activities of collagen and bioceramics, such as hydroxyapatite, in relation to bone cells, such as osteoblasts, with and without a high magnetic field of 14 T were examined using observation of collagen gel contractions. The morphology of contracted collagen gel with whisker-like hydroxyapatite after 48 hours was ellipsoidal with the major axis parallel to the collagen orientation direction and perpendicular to the applied magnetic field of 14 T. On the other hand, the gels with whisker-like hydroxyapatite under a high magnetic field also showed a contraction after 74 hours, and the shape of the contracted gel was a perfect circle. The behavior of collagen gel contractions was applicable to the synthesis of biomaterials.
