2018 Volume 4 Issue 1 Pages 49-53
An antihypertensive effect of chotosan has been reported, but few clinical cases have been described. We encountered a patient with refractory hypertension in subarachnoid hemorrhage, for which chotosan was effective. A 39–year–old man presented subarachnoid hemorrhage due to rupture of an anterior communicating aneurysm and underwent coil embolization. Intravenous and oral administration of several antihypertensive drugs were concomitantly performed after surgery, but blood pressure control was poor. However, administration of chotosan markedly reduced blood pressure and enabled blood pressure control with oral antihypertensive drugs alone. This case suggests that concomitant administration of chotosan may be considered for a patient in whom the effect of antihypertensive drugs is insufficient.
