Clinical effectiveness of jidabokuippo for the swelling after brain tumor surgery

Abstract

Jidabokuippo consists of seven herbal medicines and is reportedly effective for alleviating swelling and pain after trauma. In this study, we investigated the effectiveness of jidabokuippo after craniotomy of brain tumor surgery. To examine the effectiveness of jidabokuippo for brain tumor surgery patients, we　retrospectively studied 120 cases prescribed jidabokuippo after craniotomy in our hospital between 2016 and 2020. Background characteristics of 120 cases were: glioma (38 cases), meningioma (28 cases), metastatic brain tumor (22 cases), CP angle tumor (12 cases) and others (22 cases). In all cases, pain and swelling improved significantly after taking jidabokuippo (Wilcoxon signed rank test, p<0.001). After brain tumor surgery, jidabokuippo improved sub­jective symptoms of pain and swelling. Jidabokuippo represents a promising herbal medicine for the treatment of pain and swelling after brain tumor surgery.