Transient Thrombocytopenia after Incompatible Red Blood Transfusion in an Infant Girl with Autoimmune Hemolytic Anemia

抄録

We report on 5-month-old girl with severe autoimmune hemolytic anemia (hemoglobin 2.9 g/dl, positive direct Coombs test) in whom thrombocytopenia developed after red blood cell transfusion. The platelet count was 62.1 × 10⁴/mm³ on admission and rapidly fell to 6.0 × 10⁴/mm³ rapidly after transfusion of incompatible red blood cells with intravenous predonisolone administration. No increased hemolysis or alloimmunization was observed after transfusion. The platelet count and hemoglobin levels gradually improved over 8 weeks with corticosteroid therapy. We suspect that the thrombocytopenia in our patient was transfusion-induced.