Journal of Nippon Medical School
Online ISSN : 1347-3409
Print ISSN : 1345-4676
ISSN-L : 1345-4676
Case Reports
Small Cell Lung Cancer with Sarcoidosis in Spontaneous Remission: A Case Report
Yumeka SasakiYasuhiko KogaNorimitsu KasaharaYoshimasa HachisuKeisuke MurataHiroaki TsurumakiMasakiyo YatomiYusuke TsukagoshiYuri SawadaReiko SakuraiAkihiro OnoNoriaki SunagaKyoichi KairaJunko HiratoToshitaka MaenoKunio DobashiTakeshi Hisada
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2018 年 85 巻 5 号 p. 291-296

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A 69-year-old woman was diagnosed with sarcoidosis, which was not treated with corticosteroid therapy. Her levels of angiotensin converting enzyme decreased significantly over 4 years and a mass lesion was detected near the lower part of her left main bronchus, and diagnosed as small cell lung cancer (SCLC). Treatment of the SCLC with a series of chemotherapeutic agents produced excellent results. The pulmonary sarcoidosis did not show any deterioration despite the frequent use of amrubicin, which is known to be a cause of interstitial pneumonia. This is a case report of SCLC complicated with sarcoidosis in a stage of spontaneous remission, possibly suggesting an association between sarcoidosis and tumor immunity, since recent reports have suggested that immune checkpoint inhibitors might be involved in the development of sarcoidosis.

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© 2018 by the Medical Association of Nippon Medical School
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