Journal of Nippon Medical School
Online ISSN : 1347-3409
Print ISSN : 1345-4676
ISSN-L : 1345-4676

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A case of fever, impaired consciousness, and psychosis caused by nitrous oxide abuse and misdiagnosed as acute meningitis
Naoto MatsudaHiroaki WakakuriKazuyuki UeharaHideya HyodoToshihiko OharaMasahiro Yasutake
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ジャーナル フリー 早期公開

論文ID: JNMS.2023_90-505

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Nitrous oxide (N2O) is readily available, and its abuse for recreational purposes has become a social problem. In Japan, where N2O is strictly prohibited for non-medical use, abuse is often overlooked due to a lack of experience in the field. N2O abuse causes various long-term symptoms, including vitamin B12 deficiency, myelopathy, myeloneuropathy, subacute combined degeneration, mood changes, and psychosis. The diagnosis of N2O abuse is difficult due to the compound's short half-life and rapid elimination through the lungs. This report describes a case of fever and impaired consciousness in a patient with a history of N2O abuse.

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