膀胱充満と排尿時にみられる自律神経反射

抄録

Suppression of the micturition desire causes strain on the whole body. The cerebral apoplexy and the so-colled micturition syncope often occur during urination.
These facts indicate that the whole body can be influenced by the impulses arising in and/or around the urinary bladder. The present study was attempted to elucidate the mechanism underlying this, and the following results were obtainedon the human subjects.
1) Artificial distension of the bladder by physiological saline solution induced the following changes. Namely, the R-R interval of ECG became shorter; the blood pressure extremely higher; the plethysmographic fluctuation less; the activities of the plasma renin and plasma angiotensin I &II higher. But no changes were observed in the activities of the plasma aldosterone and the plasma cortisol.
2) The changes mentioned above were not observedif the wall of the bladder was anestetized with lidocaine hydrochloride.
3) Based on these results, it was considered that the distension of the bladder influences the whole body through autonomic reflexes.