抄録
It is well recognized clinically that there are some instances of the senile hypertension which remained within normal blood pressure after discontinuation of the long -term administration of the antihypertensive drugs. With a purpose of clarifying the mechanism involved the above -mentioned fact, the author has investigated the left cardiac function, using the time phase cont -raction which was made available through the functional cardiogram.
Seventeen cases of the normotensive elderly subjects served as control. Twenty-three cases of the hypertensive subjects which showed elevation of the blood pressure and 17 cases which failed to show the elevation of the blood pressure were investigated.
1) Related to the LVETc, the significant shortening was observed in the group which showed no elevation of the BP., in comparison with the group which showed reelevation of the blood pressure. The LVETc was also significantly shortened in the former group, comparing to the senile hypertensive group. However no significant difference was noted in the group which showed reelevation of the BP. and senile hypertensive group.
2) Related to the ICT and PEP, the group which showed no elevation of the blood pressure disclosed significant prolongation, comparing to the group which showed reelevation of the blood pressure, and the senile hypertensive group. However, no significant difference was discernible in the group which showed reelevation of the blood pressure and senile hypertensive group respectively.
3) Related to the LVET/ICT and LVET/PEP, the significant low value was noted in the group which showed no elevation of the blood pressure, in comparison with the group which showed reelevation of the blood pressure and senile hypertensive group respectively. However, no significant difference was discernible between the group which showed reelevation of the blood pressure after discontinuation of the drugs and senile hypertensive group.
4) Related to the Pd/ICT, the significant low value was noted in the group which showed no elevation of the blood pressure, in comparison with the group which showed reelevation of the blood pressure and senile hypertensive group. However, no significant difference is encountered in the group which showed reelevation of the blood pressure after discontinuation of the drugs and the senile hypertensive group.
5) Based on these observations, the group which showed no elevation of the blood pressure after discontinuation of the dring therapy might indicate the disfunction of cardiac pumpingmechanism as well as reduced contractility, indicating the evidences of the heart failure.
