抄録
The aim of this work was to synthesize and study complexes of M (CO) 3+ with dithiocarbamate ligands included morpholine moiety which have high affinity to melanoma. The corresponding complexes of rhenium (A and B) were obtained by simultaneous mixing of bidentate (dithiocarbamate) and monodentate (isonitrile) ligands with [Re (CO) 3Br3][NEt4]2. For the comparative evaluation of these technetium-99m complexes for diagnostics of melanoma the study of affinity of these complexes to the cells of melanoma B 16 in vitro was carried out.
