PARTICIPATION OF VITAMIN B₆ IN THE BIOSYNTHESIS OF COENZYME A

Abstract

1. A marked decrease in liver CoA was observed in rats maintained on VB₆-deficient diets.
2. The enzymes fractionally prepared from the liver of rats and pigs according to the method of Hoagland and Novelli were employed for the biosynthesis of CoA, and VB₆ appears to be involved in the synthesis of pantetheine from pantothenate.