Journal of Nutritional Science and Vitaminology
Online ISSN : 1881-7742
Print ISSN : 0301-4800
ISSN-L : 0301-4800
IN VIVO INCORPORATION OF GLUCOSE CARBON INTO BRAIN AND LIVER PROTEINS IN BIOTIN-DEFICIENT RATS
Hemmige N. BHAGAVANDavid B. COURSIN
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1976 Volume 22 Issue 2 Pages 79-87

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Abstract

The in vivo utilization of D-[U-14C] glucose with particular reference to its incorporation into brain and liver proteins was studied in biotin-deficient rats. The data show a significant reduction in the incorporation of glucose carbon into brain and liver proteins. A disturbance in the intermediary metabolism of glucose appears to be one of the factors responsible for the decreased incorporation of the label into proteins in biotin deficiency.

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