OXIDATION PRODUCTS OF N-METHYL-2, 2, 7, 8-TETRAMETHYL-6-AMINO-CHROMAN, A MODEL COMPOUND OF N-METHYL-γ-TOCOPHER-AMINE WITH POTASSIUM FERRICYANIDE

Abstract

N-Methyl-2, 2, 7, 8-tetramethyl-6-amino-chroman, a model compound of N-methyl-γ-tocopheramine, was submitted to an oxidation study with alkaline potassium ferricyanide. As oxidative products, 2, 2, 7, 8-tetramethyl-6-amino-chroman and dimeric (VI) were identified. Also, a trace of compound C which might be a azochroman was detected. It was concluded that an N radical formation is necessary to take the role of a biological antioxidant of N-methyl-γ-tocopheramine.