Antibacterial Compounds of Licorice against Upper Airway Respiratory Tract Pathogens

Yasuo TANAKA; Hiroe KIKUZAKI; Seiji FUKUDA; Nobuji NAKATANI

doi:10.3177/jnsv.47.270

Yasuo TANAKA, Hiroe KIKUZAKI, Seiji FUKUDA, Nobuji NAKATANI

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Keywords: licorice, Glycyrrhiza uralensis, antibacterial activity, upper airway respiratory tract pathogens

JOURNAL FREE ACCESS

2001 Volume 47 Issue 3 Pages 270-273

DOI https://doi.org/10.3177/jnsv.47.270

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Abstract

The antibacterial activity of compounds obtained from licorice was measured against upper airway respiratory tract bacteria such as Streptococcus pyogenes, Kaemophilus irnfluenzae and Moraxella catarrhalis, Among the tested compounds, licoricidin exhibited the highest activity against all tested microorganisms with an MIC of 12.5, μg/mL. Three coumarin derivatives, glycyrol, glycyrin and glycycoumarin also showed antibacterial activ-ity.

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