The Effect of Polysaccharides Extracted from the Calf Bone Marrow on the Bone-Marrow Tissue Culture

Part 2. The Effect of Polysaccharides with addition of Sera from Anemic Patients and Bone Marrow Inhibitory Agents on the Bone Marrow Tissue Culture of Rabbits

Abstract

The author studied the effects of the addition of the polysaccharides extracted from the bone marrow in combination with sera of various anemic patients and inhibitory agents of bone marrow on the bone-marrow tissue culture both in fluid medium and in cover-slip method; and obtained the following results:
1. The acceleration of the bone marrow function by polysaccharides extracted from the bone marrow acts antagonistically the action of the anemia inducing factors in sera of aplastic anemia, Banti's disease, and chronic myelogenous leukemia, and in cases it reactivates the bone-marrow function above that of the normal.
2. Even in the case of combination with Carzinophilin or nitromine, such an accelerative action of polysaccharides, antagonistically against the action of these inhibitory agents on the bone marrow, reactivates the bone-marrow function, but in this instance the antagonistic power is relatively less than that in the case of the above.