A study on the oxidative shunt of glucose metabolism in the brain

Part 1. Production of ribose-5-phosphate from 6-phosphogluconate by irrigation method

Abstract

An experimental study was performed by (INOUE'S) irrigating method in the living brain of decapitated rabbits. Adding 6 phosphogluconate into the irrigating fluid, pentose was found to be produced. Then the rabbit brain was irrigated with 6-P³²-G and the reactive products after irrigation were analysed with paperautoradiography. In the reactive products ribose-5-phosphate was proved.