Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
Online ISSN : 1882-4528
Print ISSN : 0030-1558
Nitrogen Metabolism of the Brain
Part 16 Studies on the Activities of Glutamine Synthesis in the Brain Extract of the Rats Treated with Various Methods
Tsuneko Ota
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1959 Volume 71 Issue 5-1 Pages 2139-2143

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Abstract
The activities of glutamine synthesis in the brain extract of the rat treated with various methods, were observed by means of the Conway's microdiffusion analysis. The brain extract were incubated at 37°C, pH 7.2 for 25 minutes under aerobic condition.
1) The activity of glutamine synthesis in the rat' brain extract treated with intensive electro-shock series, averaged 2.21 μM per tube and showed an increase in comparison with the control value.
2) In the insulin shock series it was 1.04 μM per tube in average and was a lower level than the control value.
3) The activity averaged 0.91 μM per tube in the Philopon (Pervitin) administration series.
4) In the Ritalin treatment series its average activity was 1.10 μM per tube and so Philopon and Ritalin decreased in its comparative activities with the control.
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