Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
Online ISSN : 1882-4528
Print ISSN : 0030-1558
The Influences of Various Hormones on the Function of Megakaryocytes By Means of Bone-Marrow Tissue Culture
Part. 4. Influences of ACTH, Cortisone, and Predonisolone on the Megakaryoycte Function in Various Blood Diseases
Hideo Nishishita
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1959 Volume 71 Issue 5-1 Pages 2377-2391

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Abstract
By means of bone-marrow tissue culture the author studied the influences of various hormones such as ACTH, cortisone, and predonisolone on the megakaryocyte function in various blood diseases, and obtained the following results:
1. ACTH has been found to act most effectively to restore the megakaryocyte function in idiopathic thrombocytopenic purpura, and cortisone and predonisolone follow in the effectiveness in that order.
2. Cortisone has been found to act most effectively to restore the megakaryocyte functon in aplastic anemia, followed by predonisolone and ACTH in the effectiveness in the descending order.
3. Predonisolone acts most effectively in restoring the megakaryocyte function in Banti's disease, follewed by ACTH and cortisone in the effectiveness in the order mentioned.
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