Clinico-Pathological Studies on the Urinary bladder Neoplasms

Abstract

Recently, much necessities have been required in regard to the early diagnosis and treatments for the neoplasms of the urinary bladder. From this point of, 242 cases of the bladder neoplasms over the last 11 years were studied clinically and pathologically for the purpose of potential curability.
Statistically or epidemiologically, the number of the neoplasms of the urinary bladder is increasing year by year, and 5 interesting cases of an infant bladder neoplasms were observed.
Operations have been done on 52 cases of 242 cases and the numbers of each cases were as followed: segmental resection 38 cases, cystectomy 8 cases, transvesical coagulation 6 cases.
Histopathological and histochemical studies were performed on 46 cases of 52 cases and showed the adaptation of Ichikaw-Tuji's classification based on Broders-Jwett's is suitable for the purpose of grading and infiltrating of the urinary bladder neoplasms.
Pathologically, Broder's classification is still much reliable as it based on the cellular activities, and the degree of infitration is rather paralleled to the degree of malignancy.
Although, small blood vessels were observed in tumor while fibrous or papillary proliferation of transitional cell epithelium appeared, and in the cases of high malignancy, the loss of vascular channel appeared and also showed the high infiltration.
Histochemically, fatts were increasing, polysaccharides were decreasing and nucleic acid, enzymes were much reactive with increasing of malignancy.