Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
Online ISSN : 1882-4528
Print ISSN : 0030-1558
Metabolism of γ-Aminobutyric Acid
Part 1. Incorporation of γ-Aminobutyric Acid into Mouse Organs
Kazuaki Uno
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1961 Volume 73 Issue 10-12 Pages 771-775

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Abstract
An attempt was made to make a study on an incorporation of GABA with brain when it was administered to a mouse abdominal cavity.
1) When 0.5 mg per body gram weight of GABA was administered, the content in the mouse brain was not changed, although the one in the liver was rapidly and yet temporarily increa- sed.
2) A one week successive administration, 0.3 mg per body gram weight of daily dosage could not make any change of the content in the brain.
3) A study with 14C-GABA revealed a rapid temporary incorporation with the liver and the kidney and, in contrast, considerbly little with the brain.
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© Okayama Medical Association
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