SV 40誘発腫瘍細胞の長期培養による変化について
1971 年 83 巻 7-8 号 p. 229-233
詳細
1971 年 83 巻 7-8 号 p. 229-233
SV 40 induced hamster tumor cells were cultured in vitro for long terms. Morphological changes and vicissitudes of T antigen and oncogenity were examined in cultured cells. Morphological appearance. has changed from fibroblastic to epitheloid. T antigen and oncogenicity decreased with increasing time, both of which at last disappeared at about 300 days of culture. The significance of the findings is discussed.
