Single Nucleotide Polymorphisms (SNPs) Detected in the gbpC Gene Coding Region of Streptococcus mutans

Yutaka Sato; Kazuko Okamoto-Shibayama; Akiyoshi Kagami; Yasuhito Yamamoto; Harutoshi Kizaki

doi:10.2330/joralbiosci.47.171

SHORT COMMUNICATION

Single Nucleotide Polymorphisms (SNPs) Detected in the gbpC Gene Coding Region of Streptococcus mutans

Yutaka Sato, Kazuko Okamoto-Shibayama, Akiyoshi Kagami, Yasuhito Yamamoto, Harutoshi Kizaki

著者情報

キーワード: Streptococcus mutans, glucan-binding protein C, the gbpC gene, single nucleotide polymorphisms (SNPs)

ジャーナル認証あり

2005 年 47 巻 2 号 p. 171-174

DOI https://doi.org/10.2330/joralbiosci.47.171

詳細

抄録

Streptococcus mutans glucan-binding protein C encoded by the gbpC gene is an important virulent factor in human dental caries. However, a nonsense mutation and several nucleotide substitutions in the gbpC gene have been detected in strain GS-5. Therefore, gbpC nucleotide sequences from 17 additional S. mutans strains were determined and single nucleotide polymorphisms were detected. Both conserved and polymorphic regions of the gbpC gene will be useful for estimation of functional domains of GbpC protein and identification of S. mutans strains.

責任著者(Corresponding author)

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