Two Cases of Anisometropic Amblyopia With Mittendorf Spot and Severe Higher Order Aberrations

Abstract

[Purpose] We reported two cases of anisometropic amblyopia with Mittendorf spot that achieved good visual acuity and stereo acuity by nonsurgical amblyopic treatment.
[Cases] The patient in case 1 was a 3-year-old boy with a 0.8 mm-diameter Mittendorf spot in the left eye. Visual acuity after cycloplegia was RV = (1.0×+3.50 D) and LV = (0.5×+5.00 D, cyl-2.50 D 60°). Higher order aberrations by Wave-Front Analyzer KR-1W^® (TOPCON) were 0.052 μm (right) and 0.826 μm (left). After refractive correction and occlusion therapy, he achieved the best corrected visual acuity of 1.0 and stereo acuity of 60 second of arc.
  The patient in case 2 was an 11-year-old girl with a 1.6 mm-diameter Mittendorf spot in the right eye. Visual acuity after cycloplegia was RV = (0.6×+2.50 D, cyl-1.50 D 155°) and LV = (1.5×+0.50 D, cyl-0.75 D 180°). Higher order aberrations were 0.231 μm (right) and 0.108 μm (left). After refractive correction and occlusion therapy, she obtained the best corrected visual acuity of 1.2 and stereo acuity of 60 second of arc.
[Conclusion] In amblyopic eyes with Mittendorf spot and large amount of higher order aberrations, amblyopic treatment could be effective even if the eyes are anisometropic.