Evaluation of the Skin-Roughness Caused by Aqueous Solution of Surfactants

Relation between the Inhibition of Invertase Activity by Surfactant and the Skin-Roughness

Abstract

Protein denaturalization in the aqueous solution of surfactant was discussed by measuring the degree of the inhibition of invertase activity. Evaluation of the human skin-roughness was performed by the dropping method and the immersion method. A strong correlation was observed between the inhibition o invertase activity by surfactants and the skin-roughness.
This screening method is an excellently valuable selecting mild surfactans for skin.