Abstract
5-Cyclohexadecenone, having musk-like odor, is prepared from cyclododecanone via four new steps; chlorination, Grignard reaction with vinylmagnesium chloride and rearrangement with aluminium isopropoxide, revinylation with vinylmagnesium chloride and oxy-Cope rearrangement. 5-Cyclohexadecenone is also prepared from cyclododecane epoxide by the combination of vinylation and chromic oxidation.
