Abstract
Several methodologies for making liposome more stable and more cell specific are introduced in this review article. They involve reconstitutions of glycoproteins or glycolipids into liposomal membranes and coating the outermost surface of liposomal membranes with naturally occurring polysaccharides. Results in the in vitro and in vivo evaluation of such the modified liposomes are also described from the view points of their chemical, physicochemical, and biochemical stabilities and cell compatibility and specificity.
In addition, the usefulness of these glyco-conjugated liposomes, for example, in receptormediated drug targeting or liposomal vaccines in medicine and serum free cell culture in biotechnology, is briefly introduced.
