Abstract
Synthesis and properties of a series of fluoroalkylated oligomers by using fluoroalkanoyl peroxides have been reviewed. The synthetic methods of fluoroalkylated acrylic acid, nonionic, and cationic oligomers were illustrated. These fluoroalkylated oligomers, in particular, fluoroalkylated acrylic acid, nonionic, and cationic oligomers were in general shown to become soluble not only in water but also in common organic solvents such as methanol, ethanol, dimethyl sulfoxide, benzene and toluene. These fluoroalkylated oligomers have quite unique structure that fluoroalkyl groups are substituted only on the both terminals of oligomer chain, and can be regarded as double-chain type surfactant. They exhibit excellent surface active properties attributable to fluoroalkyl groups, such as quite low surface and interfacial tension, and anti-foaming property, and so on.
Fluoroalkylated acrylic acid homo-and co-oligomers were demonstrated to exhibit a potent anti-HIV-1 activity in vitro. Furthermore, fluoroalkylated cationic oligomers were found to have an antibacterial activity. Therefore, these fluoroalkylated acrylic acid and cationic oligomers have been widely applicable to various fields as the novel functional materials which possess both a unique property imparted by fluorine and an anti-HIV-1 or antibacterial activity.
