Abstract
The application of supercritical fluid chromatography (SFC) to lipid separation is reviewed. Both capillary and packed column SFC have been extensively used in the separation of nonpolar and less polar lipids, and the published data are summarized in this paper. The separation behavior of fatty acids and triacylglycerols in SFC is discussed in comparison with that in gas chromatography and liquid chromatography. This report also describes some applications of preparative SFC to the fractionation of high value constituents contained in natural lipids.