Abstract
The biotransformation of 4-tert-butylcyclohexanone was conducted using ten anthracnose fungi as biocatalysts. The 4-tert-butylcyclohexanone was reduced to the corresponding cis- and trans-alcohols. The biotransformation of 4-tert-butylcyclohexanone resulted mainly in its transformation to trans-4-alcohol, using Colletotrichum lagenarium, C. atramentarium MAFF 712102, C. fragariae, C. graminicola MAFF 305460, C. lindemuthianum (C-3) and C. lindemuthianum (C-13). The cis- and trans-alcohol products were obtained at a ratio of 1.0 : 6.0 with stereoselectivity by Colletotrichum lagenarium after 7 days incubation. The cis-alcohol was formed with stereoselectivity by Glomerella cingulata, C. lindemuthianum (C-1), C. trifolii MAFF 305389 and C. dematium MAFF 410046.
