Supramolecular Structures of Functionality Vesicles

Niosome Formation of Nonionic Amphiphiles and Physico-Chemical Properties in Aqueous Dispersion

Abstract

Aggregate properties of aqueous solutions of surfactants, characterization of model membranes, methods for the preparation of vesicles and vesicle-forming surfactants are reviewed in the present study. Nonionic amphiphiles are widely regarded as synthetic tailor-made lipids in consideration of their safty and ease of molecular structural design. In search for vesicle-forming substances with safe physiological properties, good storage stability and ease of preparation, poly (oxyethylene) (10) hydrogenated castor oil was found to meet these requirements. Vesicle formation of poly (oxyethylene) hydrogenated castor oil and physico-chemical properties in aqueous dispersion are discussed in the following.