The Journal of Nihon University School of Dentistry
Online ISSN : 1884-2984
Print ISSN : 0029-0432
ISSN-L : 0029-0432
Studies on the Antidotal Action of Drugs
Part 1 Vitamin C and Its Antidotal Effect against Alcoholic and Nicotine Poisoning
田村 豊幸井上 博飯田 高史大野 洋光
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1969 年 11 巻 4 号 p. 149-151

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Vitamin C in its various preparations is one of the most commonly administered drugs in dentistry. In connection with many researches related to the poisoning of many pharmaceuticals, research endeavors are also active in the antidotal action of these drugs.
TAMURA, one of the present authors, published his experimental studies on the elimination of an injurious by-effect of promine [1, 2] and also those dealing with leucine against caffeine [3], substances having antidotal effects on morphine and nicotine [4] and anti-alcoholic agent [5].
Although the possibility of vitamin C poisoning has drawn the attention of medical and dental profession for a long time, almost nothing is known about its effect when administered conjointly with some form of amino acid.
In the present report, the authors are concerned with the antidotal mechanism of vitamin C and glucose-cysteine against acetaldehyde responsible for the alcoholism and nicotine, a potent factor in the nicotinism.
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