抄録
With aim of histological study on the changes and response processes of surrounding tissue to endosseous functioning dental implant, we had inserted the blade implant in the mandibular molar region of Macacus Irus with the identical technique being applied clinically. Applying usual mastication force to the implant which served as the posterior abutment of fixed bridge and feeding for an expanded span of period, the animals were closely observed.
As a primary report of the present experiment, macroscopic, radiographic, and microscopic findings of one to six months P.O. cases were obtained. Summary of the findings is as follows :
1) By six months P.O., a thin collagenous layer, neo-intima of approximately 1/10mm in thickness had uniformally developed between the implant and its surrounding bone. The proportion of cells and fibres and thickness of neointima had changed with the passing of time after operation.
2) Neointima was osteogenetic tissue of fibrous bone which regenerated around the implant [26, 27, 28, 29].
3) The inner layer of gingival sulcus around the implant neck came from extension of gingiva, lacking in papilla, and underlined with neointima which was lamina propria. Under-growth of epithelium did not develop deeper than alveolar bone crest.
4) There was an infiltration of chronic inflammatory cells to the base of gingival sulcus and to underlining collagen layer to the same extent as that which affected the area around the natural tooth used as a control. There was no finding of inflammation at any other site nor was there any rejection response, foreign body reaction, and sequestrume of bone.
5) Neointima was in intimate contact with the implant. New bone and neointima surrounded the implant and grew into the vents. It can be considered that they had played an important role of effective stabilization and support of the implant.
6) The arrangement of fibres in neointima and regeneration of new bone showed a definite order along the implant by one to six months after operation.
7) Periapical X-ray films showed suitable informations which were interpreted as changes in the bone and neointima.
The above findings are very encouraging to the clinical application of blade implants. However, final conclusion must be reserved until more observations of longer term follow-up results have been gathered and evaluated.
