Mice and similar subjects were used in a series of tests where they were placed in a shaking apparatus of simple mechanism and the state of being train-sick was artificially generated. They could not grasp a glass rod immediately after this state but when anti-train drugs were pre-medicatively administered, the time before they recovered an ability to grasp the rod was much reduced. From this, it has been established that the use of a shaking apparatus and a glass rod proves effective in an examination of effects attributed to these anti-train sick agents which are now commer cially available.
In this connection, it was also found out that effects of chlorpromazine which is accepted as anti-shock agent work adversely on the generation of vertigo in the case of a fall. It is thought that the study on this subject furnishes a useful insight in the training of personnel engaged in the air transportation where they are faced with the necessity of parachuting down from a considerable height.
It may be added that a part of the present report was read before the Tokyo meeting of 23rd Japan Pharmacological Society Congress, held in November 1961.
