Abstract
For five patients in the acute phase after stroke onset, we did not constrain the non-paralyzed arm in the real world, but employed intensive upper-extremity training combined with supplementary methods for two hours per day for about three weeks. This study investigated the efficacy and safety of combined intervention including the intensive training in acute phase from stroke onset for improving affected upper-extremity function and use in activities of daily living. Results indicate significant improvements in the affected upper-extremity function and the amount and quality of arm use in real world. In addition, no adverse events were observed during the intervention period. Therefore, these results suggest that shortened intensive training in the acute phase from the onset of stroke might be a meaningful method to improve the affected upper-extremity function and use in activities of daily living. However, to completely demonstrate the effect of this intervention protocol in the acute phase from stroke onset, we will have to investigate using randomized controlled trials with control groups in the future.
